Tetrahedron

A New Route to γ-Arylidenebutyrolactones via a tandem carbopalladation-heterocyclisation sequence: a formal synthesis of U-68,215

M Cavicchioli, S Decortiat, D Bouyssi, J Goré, G Balme

Index: Cavicchioli, Marcello; Decortiat, Sylvie; Bouyssi, Didier; Gore, Jacques; Balme, Genevieve Tetrahedron, 1996 , vol. 52, # 35 p. 11463 - 11478

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Citation Number: 42

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Benzo-annulated enol lactones are obtained in good yields from pentynoic acids 3- or 5-substituted with an iodo-aryl moiety by palladium-catalyzed cyclization of their potassium carboxylates. Using this approach, an efficient new route to U-68,215 is described. ... The application of this ...