e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

The Reaction of 6-Methoxy-8-aminoquinoline with Alkylamino-alkyl Halides1, 2

RC Elderfield, LE Rubin

Index: Elderfield; Rubin Journal of the American Chemical Society, 1953 , vol. 75, p. 2963,2969

Full Text: HTML

Citation Number: 2

Abstract

The acid dissociation constants for the quinoline nitrogen of 6; pH range of 2.5-5.5 have been investigated. 8-aminoquinoline by an isopropylaminoalkyl halide has been determined. have been calculated for each reaction. fects cannot be explained solely on the basis of pH. quinoline diphosphate (CN-1105) has been described. methoxy-8- aminoquinoline and the terminal aliphatic amino groups of pentaquine, isopentaquine ...

8-Amino-6-methoxyquinoline Structure

8-Amino-6-metho...

N/A Structure

~%

pentaquine Structure

8-Amino-6-methoxyquinoline Structure

8-Amino-6-metho...

N/A Structure

Water Structure

~%

pentaquine Structure

8-Amino-6-methoxyquinoline Structure

8-Amino-6-metho...

(5-bromo-pentyl)-isopropyl-amine Structure

(5-bromo-pentyl...

Water Structure

~%

pentaquine Structure

8-Amino-6-methoxyquinoline Structure

8-Amino-6-metho...

(5-bromo-pentyl)-isopropyl-amine Structure

(5-bromo-pentyl...

~%

pentaquine Structure

8-Amino-6-methoxyquinoline Structure

8-Amino-6-metho...

~%

N-(6-methoxyquinolin-8-yl)-N-propan-2-yl-pentane-1,4-diamine Structure

N-(6-methoxyqui...

8-Amino-6-methoxyquinoline Structure

8-Amino-6-metho...

4-bromo-N-propan-2-yl-pentan-1-amine Structure

4-bromo-N-propa...

Water Structure

~%

N-(6-methoxyquinolin-8-yl)-N-propan-2-yl-pentane-1,4-diamine Structure

N-(6-methoxyqui...

8-aminoquinolines as anticoccidials-part III

[Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430]

8-aminoquinolines as anticoccidials-part III

[Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430]

8-aminoquinolines as anticoccidials-part III

[Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430]

8-aminoquinolines as anticoccidials-part III

[Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430]

8-aminoquinolines as anticoccidials-part III

[Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430]