Abstract: Trimethylsilyl enol ethers (1) reacted with l-ethoxycarbonylpyridinium chloride (2) at 4-position with high rezoselectivity to afford l-ethoxycarbonyl-4-(2-oxoalkyl)-1, 4_dihydropyridines(2) in 42-8'7% yields. When 2, 2, 2-trichloroethyl chloroformate was employed, yields of the corresponding 1, 4_dihydropyridines(g) were higher (80-100% yields). $ and 8 were oxidized by oxygen or AgN03 to give 4-(2-oxoalkyl) pyridines (1,: 30- ...
![[(1-(ethyl)propenyl)oxy]trimethylsilane Structure](https://image.chemsrc.com/caspic/468/17510-47-3.png)