Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3, 4-dihydroxytamoxifen-o-quinone

F Zhang, PW Fan, X Liu, L Shen…

Index: McCague, Raymond; Potter, Gerard A.; Jarman, Michael Organic Preparations and Procedures International, 1994 , vol. 26, # 3 p. 343 - 346

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Citation Number: 82

Abstract

... 4-Hydroxytamoxifen was synthesized according to the literature procedure (17). ... The combined organic layers were washed with saturated NaHCO 3 (80 mL) and saturated NaCl (80 mL) and ... for 15 min at 60 °C. After filtration, the solution was concentrated to a final volume of 1 ...