Synlett

Novel and unexpected deamination during the palladium-catalysed cross-coupling of haloanilines and arylboronic acids

M Hird, AJ Seed, KJ Toyne

Index: Hird, Michael; Seed, Alexander J.; Toyne, Kenneth J. Synlett, 1999 , # 4 p. 438 - 440

Full Text: HTML

Citation Number: 10

Abstract

Abstract: Palladium-catalysed cross-coupling reactions involving haloanilines and arylboronic acids produce the expected biaryl products, but additionally a substantial quantity of the corresponding deaminated biaryl is also generated which constitutes a novel synthetic methodology. Key words: deamination, palladium-catalysed, cross-coupling, arylboronic acids

 Related Synthetic Route
4-Cyanophenylboronic acid Structure

126747-14-6

4-Cyanophenylbo...

4-Iodoaniline Structure

540-37-4

4-Iodoaniline

~39%

4-Cyanobiphenyl Structure

2920-38-9

4-Cyanobiphenyl

4-Amino-4'-cyanobiphenyl Structure

4854-84-6

4-Amino-4'-cyan...

(4-Pentylphenyl)boronic acid Structure

121219-12-3

(4-Pentylphenyl...

4-Bromoaniline Structure

106-40-1

4-Bromoaniline

~45%

4-Pentylbiphenyl Structure

7116-96-3

4-Pentylbiphenyl

4-(4-pentylphenyl)aniline Structure

60040-14-4

4-(4-pentylphen...

(4-Pentylphenyl)boronic acid Structure

121219-12-3

(4-Pentylphenyl...

4-Iodoaniline Structure

540-37-4

4-Iodoaniline

~33%

4-Pentylbiphenyl Structure

7116-96-3

4-Pentylbiphenyl

4-(4-pentylphenyl)aniline Structure

60040-14-4

4-(4-pentylphen...

4-Cyanophenylboronic acid Structure

126747-14-6

4-Cyanophenylbo...

4-Iodoaniline Structure

540-37-4

4-Iodoaniline

~41%

4-Cyanobiphenyl Structure

2920-38-9

4-Cyanobiphenyl

4-Amino-4'-cyanobiphenyl Structure

4854-84-6

4-Amino-4'-cyan...


Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved