Synlett

Novel and unexpected deamination during the palladium-catalysed cross-coupling of haloanilines and arylboronic acids

M Hird, AJ Seed, KJ Toyne

Index: Hird, Michael; Seed, Alexander J.; Toyne, Kenneth J. Synlett, 1999 , # 4 p. 438 - 440

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Citation Number: 10

Abstract

Abstract: Palladium-catalysed cross-coupling reactions involving haloanilines and arylboronic acids produce the expected biaryl products, but additionally a substantial quantity of the corresponding deaminated biaryl is also generated which constitutes a novel synthetic methodology. Key words: deamination, palladium-catalysed, cross-coupling, arylboronic acids