Abstract cis and trans-2, 6-Bis [bromomercuriomethyl] piperazines II which bear equal or different substituents at each nitrogen are obtained in the reaction of N-substituted diallylamines with mercury (II) acetate and aryl-amines followed by a double decomposition process with potassium bromide. Their reduction with sodium borohydride lead to the corresponding 1, 4-disubstituted cis-and trans-2, 6-dimethylpiperazines III. Steric factors ...