Mercuric acetate cyclization of 4-(pyrrolylmethyl)-and 4-(indolylmethyl) piperidines to bridged polycyclic systems

…, D Mauleon, M Feliz, R Granados

Index: Bosch, Joan; Mauleon, David; Feliz, Miguel; Granados, Ricardo Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4836 - 4841

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Citation Number: 17

Abstract

The mercuric acetate cyclization of 4 (pyrrolylmethyl) piperidines 4 and 9 as well as of 4- (indolylmethyl) piperidines 13 and 18 to the corresponding bridged polycyclic systems is studied. When the reaction was carried out in aqueous AcOH solution, mixtures of the starting piperidine and the corresponding cyclized product were obtained. The recovery of piperidine is attributed to the mercuration of the heteroaromatic ring, which prevents the ...

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