Synthesis and antiviral activity of N [p-(R-sulfamoyl) phenyl] succinamic acids and their salts with 2-amino-2-thiazoline

D Burdulene, Z Stumbryavichyute, Z Talaikite…

Index: Burdulene; Stumbryavichyute; Talaikite; Vladyko; Boreko; Korobchenko Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 9 p. 471 - 473

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Abstract

It has been previously established [1] that the salts of N- aryl- and N-heterylsuccinamic acids with 2-amino-2-thia- zoline possess certain antiviral activity. At the same time, analogous properties were reported for some salts ofp-arni- nobenzene sulfamide derivatives [2]. ... Me NH u HN - - C (III, X); \ NH 2 N N --HN----~SI~Et (IV, Xl); ... --N O (VII, XIV); k___/ N /~ (VIII-XIV); R'=-(I-VII) , H2N S ... I Institute of Biochemistry, Vilnius, Lithuania. 2 Research Institute of ...