Pronounced Catalytic Effect of a Micellar Solution of Sodium Dodecylsulfate (SDS) Upon a Three??Component Reaction of Aldehydes, Amines, and Ketones Under …

…, F Moradgholi, F Tamaddon

Index: Jafari, Abbas Ali; Moradgholi, Fatemeh; Tamaddon, Fatemeh European Journal of Organic Chemistry, 2009 , # 8 p. 1249 - 1255

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Citation Number: 28

Abstract

Abstract A micellar solution of anionic, cationic or neutral surfactants can be used as an excellent medium for three-component Mannich reactions of aldehydes, amines, and ketones at room temperature. Sodium dodecylsulfate turned out to efficiently catalyze the reaction in neutral pure water (pH≈ 7), and the corresponding desired β-amino ketones precipitate while the reactions proceedes. This method provides a novel and improved ...