Adjuvant effects of glyceryl esters of acetoacetic acid on rectal absorption of insulin and inulin in rabbits

…, S Kim, S Morishita, A Kamada, N Yata…

Index: Nishihata; Kim; Morishita; Kamada; Yata; Higuchi Journal of pharmaceutical sciences, 1983 , vol. 72, # 3 p. 280 - 285

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Citation Number: 46

Abstract

Abstract The promoting effect of glyceryl esters of acetoacetic acid on the rectal absorption of insulin and inulin was studied. A decrease in the serum glucose level was observed in rabbits following the administration of an insulin suppository containing glyceryl-1, 3- diacetoacetate (adjuvant II) or 1, 2-isopropylideneglycerine-3-acetoacetate (adjuvant IV). The promoting effects of adjuvants II and IV on the rectal absorption of insulin and inulin ...