Synthesis

InBr3-catalyzed alkynylation and allylation of acid chlorides: A facile synthesis of alkynyl and allyl ketones

JS Yadav, BVS Reddy, MS Reddy, G Parimala

Index: Yadav; Reddy; Reddy, M. Sridhar; Parimala Synthesis, 2003 , # 15 p. 2390 - 2394

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Citation Number: 31

Abstract

Abstract Alkynylsilanes and allyltrimethylsilane undergo smooth coupling with acid chlorides in the presence of 5 mol% of indium tribromide under mild conditions to afford the corresponding α, β-acetylenic ketones and β, γ-unsaturated ketones in excellent yields in a short reaction time with high selectivity.