Studies in the 3H-quinazol-4-one series. XI. Synthesis and properties of 3-(4′-bromophenyl)-l, 2, 3, 4-tetrahydroquinazolin-4-ones

YV Kozhevnikov, OE Sattarova, VS Zalesov…

Index: Kozhevnikov, Yu. V.; Sattarova, O. E.; Zalesov, V. S.; Gradel', I. I.; Plaksina, A. N. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 11 p. 844 - 848 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 11 p. 1349 - 1353

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Abstract

A series of derivatives of 1, 2, 3, 4-tetrahydroquinazolin-4-one were found to exhibit diuretic, antiinflammatory, sedative, local anesthetic, choleric, analgetic, antihistaminic, and myorelaxant activity [1-6]. In subsequent work [7], we obtained derivatives of 4-oxo-1, 2, 3, 4- tetrahydroquinazolinone by the following scheme.