e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Stereoselective synthesis of HR 780 a new highly potent HMG-CoA reductase inhibitor

G Wess, K Kesseler, E Baader, W Bartmann, G Beck…

Index: Tetrahedron Letters, , vol. 31, # 18 p. 2545 - 2548

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Citation Number: 77

Abstract

... Downloading zip file containing 3 articles... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Tetrahedron Letters. Volume 31, Issue 18, 1990, Pages 2545–2548. Cover image Cover image. ...

tert-butyl [(4R,6S)-6-[(tert-butyldiphenylsilyloxy) methyl]-2,2-dimethyl-1,3-dioxane-4-yl]acetate Structure

tert-butyl [(4R...

~79%

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Structure

(4R-Cis)-6-Hydr...

tert-Butyl acetate Structure

tert-Butyl acetate

~%

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Structure

(4R-Cis)-6-Hydr...

N/A Structure

~%

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Structure

(4R-Cis)-6-Hydr...

(5S)-6-(tert-butyl-diphenylsilanyloxy)-5-hydroxy-3-oxohexanoic acid tert-butyl ester Structure

(5S)-6-(tert-bu...

~%

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Structure

(4R-Cis)-6-Hydr...

(4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester Structure

(4R-Cis)-6-Hydr...

~94%

tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate Structure

tert-Butyl (4R-...

tert-Butyl acetate Structure

tert-Butyl acetate

~%

tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate Structure

tert-Butyl (4R-...

N/A Structure

~%

tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate Structure

tert-Butyl (4R-...

(5S)-6-(tert-butyl-diphenylsilanyloxy)-5-hydroxy-3-oxohexanoic acid tert-butyl ester Structure

(5S)-6-(tert-bu...

~%

tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate Structure

tert-Butyl (4R-...

tert-butyl [(4R,6S)-6-[(tert-butyldiphenylsilyloxy) methyl]-2,2-dimethyl-1,3-dioxane-4-yl]acetate Structure

tert-butyl [(4R...

~%

tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate Structure

tert-Butyl (4R-...

Practical large scale synthesis of tert-butyl (3R, 5S)-6-hyd...

[Synthesis, , # 8 p. 1014 - 1018]

Synthesis of Artificial HMG-CoA Reductase Inhibitors Based o...

[Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372]

Synthesis of Artificial HMG-CoA Reductase Inhibitors Based o...

[Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372]

Synthesis of Artificial HMG-CoA Reductase Inhibitors Based o...

[Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372]

Synthesis of Artificial HMG-CoA Reductase Inhibitors Based o...

[Bulletin of the Chemical Society of Japan, , vol. 68, # 1 p. 364 - 372]