Practical Asymmetric Synthesis of RO5114436, a CCR5 Receptor Antagonist

X Huang, E O'Brien, F Thai…

Index: Organic Process Research and Development, , vol. 14, # 3 p. 592 - 599

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Citation Number: 14

Abstract

... Organic Process Research & Development. ... Methylsulfanylmethyl ether 15 (4−8%) was the major byproduct for this process. The ... trap. This procedure was carried out in the pilot plant, and the odor from DMS was well-contained. ...