The Journal of organic chemistry

Mono-and β, β-double-Heck reactions of α, β-unsaturated carbonyl compounds in aqueous media

L Botella, C Nájera

Index: Botella, Luis; Najera, Carmen Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4360 - 4369

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Citation Number: 103

Abstract

Optimized reaction conditions for the mono-and β, β-diarylation of electron-deficient alkenes in aqueous media catalyzed either by ap-hydroxyacetophenone oxime-derived palladacycle or by palladium (II) acetate under phosphine-free conditions and in the presence of (dicyclohexyl) methylamine as base are described. Regioselective monoarylation of unsubstituted and substituted α, β-unsaturated carbonyl compounds takes place with aryl ...