The reaction of Me3SiSnBu3 (1) with methyl propiolate in DMF in the presence of BnEt3NCl gave methyl 3, 3-bis (tributylstannyl) propionate (7) in high yield. Reduction of 7 with LiAlH4 followed by treatment with MOMCl gave 3, 3-bis (tributylstannyl) propanol derivative 17d in a quantitative yield, which was a useful reagent for C-3 unit elongation. Treatment of 17d with BuLi in THF in the presence of HMPA gave α-stannylated carbanion II, which reacted with ...
