Stereodefined carbon–halogen bonds are ubiquitous in nature with several natural products exhibiting this motif.[1] While the biogenetic origins of this unique chiral functionality has been a subject of several investigations in the past,[2] attempts by organic chemists to forge the carbon–halogen bond stereoselectively have largely been unsuccessful. This problem has come into focus only recently. Several elegant reports of asymmetric halogenations of ...
[Bent, Arie van der; Blommaert, Armand G. S.; Melman, Caroline T. M.; IJzerman, Adriaan P.; Wijngaarden, Ineke van; Soudijn, Willem Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1042 - 1049]
[Bent, Arie van der; Blommaert, Armand G. S.; Melman, Caroline T. M.; IJzerman, Adriaan P.; Wijngaarden, Ineke van; Soudijn, Willem Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1042 - 1049]
