Palladium??Catalyzed Allylic Arylation of Allylic Ethers with Arylboronic Acids Using Hydrazone Ligands

…, T Abe, T Koizumi, T Fujita, M Sakamoto

Index: Mino, Takashi; Kogure, Taketo; Abe, Taichi; Koizumi, Tomoko; Fujita, Tsutomu; Sakamoto, Masami European Journal of Organic Chemistry, 2013 , # 8 p. 1501 - 1505

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Citation Number: 6

Abstract

Abstract Unsymmetrical 1, 3-diarylpropenes were synthesized in good to high yields by the palladium-catalyzed allylic arylation of allylic ethers, such as a cinnamyl phenyl ether, with a variety of arylboronic acids using a hydrazone 1a–Pd (OAc) 2 system in DMAc/H 2 O. Using this catalyst, eugenol was also synthesized from allyl phenyl ether with (4-hydroxy-3- methoxyphenyl) boronic acid pinacol ester.