Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity

HW Chang, KH Jang, D Lee, HR Kang, TY Kim…

Index: Chang, Hyeun Wook; Jang, Kyoung Hwa; Lee, Doohyun; Kang, Hee Ryong; Kim, Tae-Yoon; Lee, Bong Ho; Choi, Byoung Wook; Kim, Sanghee; Shin, Jongheon Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 12 p. 3589 - 3592

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Citation Number: 27

Abstract

Polyunsaturated fatty acid-derived monoglycerides were characterized from the marine brown alga Sargassum sagamianum, collected from Jeju Island, Korea. A new compound of this structural class was isolated and determined to be 1-octadecatetraenoyl glycerol, by combined spectroscopic methods. Based on the structures and bioactivity of these compounds, a series of monoglycerides were synthesized using glycerol and various fatty ...