Tetrahedron Letters

Catalytic application of task specific ionic liquid on the synthesis of benzoquinazolinone derivatives by a multicomponent reaction

M Rahman, A Sarkar, M Ghosh, A Majee, A Hajra

Index: Rahman, Matiur; Sarkar, Anirban; Ghosh, Monoranjan; Majee, Adinath; Hajra, Alakananda Tetrahedron Letters, 2014 , vol. 55, # 1 p. 235 - 239

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Citation Number: 12

Abstract

Abstract Benzoquinazolin-2-one derivatives were synthesized by using a catalytic amount of task specific ionic liquid,[1-methyl-3-(4-sulfobutyl) imidazolium-4-methylbenzenesulfonate] through a one-pot multicomponent Biginelli reaction of α-tetralone, aldehyde, and urea/thiourea in excellent yields within a short reaction time. Mechanism studies suggest that the reaction proceeds through iminium intermediate and C2-H of the TSIL plays a ...