Abstract Several 1, 2, 3-triazole-linked glycoconjugates were efficiently synthesized via a Cu (I)-mediated 1, 3-dipolar cycloaddition with high regiospecificity and yield (≥ 85%), providing a simple and efficient route to synthesize protected and unprotected neoglycoconjugates. Introduction of a spacer between glycosyl moieties and other compounds reduces steric hindrance, promotes yield, and expands the varieties of ...