Tetrahedron Letters

Exploration of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1, 2-dihydroquinoline (PS-IIDQ) as new coupling agent for the synthesis of 8-substituted …

P Bandyopadhyay, M Sathe, P Sharma, MP Kaushik

Index: Bandyopadhyay, Prabal; Sathe, Manisha; Sharma, Pratibha; Kaushik Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4631 - 4635

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Citation Number: 8

Abstract

Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1, 2-dihydroquinoline (PS-IIDQ), a polymer supported covalent coupling reagent, was successfully employed for the first time in the synthesis of 8-substituted xanthine derivatives. PS-IIDQ was observed to be more efficient than IIDQ and polymer-supported carbodiimide (PS-EDC).