Catalytic reduction of pralidoxime in pharmaceuticals by macrocyclic Ni (II) compounds derived from orthophthalaldehyde

…, AVSS Prasad, R Rohini, V Ravinder

Index: Reddy, P. Muralidhar; Prasad, Adapa V.S.S.; Rohini, Rondla; Ravinder, Vadde Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2008 , vol. 70, # 3 p. 704 - 712

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Citation Number: 27

Abstract

Efficient catalytic method for the reduction of pralidoxime to its amine derivative by macrocyclic Ni (II) compounds has been developed. Ten macrocyclic Schiff base Ni (II) compounds were synthesized via non-template synthesis by treating the corresponding macrocycles with nickel chloride in 1: 1 ratio. The resulting compounds were characterized by elemental, IR, 1H NMR, 13C NMR, mass, electronic spectra, conductance, magnetic, ...