e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
The Friedel-Crafts Condensation of trans-2-Hydroxycyclohexaneacetic Acid Lactone with Aromatic Hydrocarbons. II. p-Xylene, Tetralin and α-Methylnaphthalene
DD Phillips, DN Chatterjee
Index: Phillips; Chatterjee Journal of the American Chemical Society, 1958 , vol. 80, p. 1911,1914
~-CH i COOA l C l~ was rationalized2 on the basis of equilibration among three of the possible carbonium ion intermediates (cf. V) before attack on the aromatic hydrocarbon took place. To gain further insight into the scope and mechanism of this reaction we have examined the behavior of three more aromatic hydrocarbons, and,