Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)

P Zhang, HR Hu, SH Bian, ZH Huang, Y Chu…

Index: Levai; Duddeck Pharmazie, 1983 , vol. 38, # 12 p. 827 - 828

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Citation Number: 10

Abstract

... Volume 61, March 2013, Pages 95–103. ... Among them, one compound called tideglusib (NP-12) is currently undergoing Phase IIb clinical trials both on AD and orphan tauopathy, and it is also the only GSK-3β inhibitor under clinical phase so far [11]. ...