… of. ALPHA.-(Acetamido) acrylates Using TRAP Trans-Chelating Chiral Bisphosphine Ligands. Remarkable Effects of Ligand P-Substituent and Hydrogen Pressure on …

R Kuwano, M Sawamura, Y Ito

Index: Kuwano; Sawamura; Ito Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 11 p. 2571 - 2578

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Citation Number: 48

Abstract

The catalytic asymmetric hydrogenation of α-(acetamido) acrylates was carried out with the rhodium complexes prepared from [Rh (cod) 2] BF 4 and trans-chelating chiral bisphosphine ligands,(S, S)-2, 2′-bis [(R)-1-(dialkylphosphino) ethyl]-1, 1′-biferrocenes [(R, R)-(S, S)- TRAPs]. In the reaction of β-unsubstituted or β-monosubstituted α-(acetamido) acrylates [(E)- RCH= C (NHAc) CO 2 Me], the selectivity for (R)-hydrogenation product increased with ...