Expedited synthesis of substituted dipyrrolo [3, 4-a: 3, 4-c] carbazole-1, 3, 4, 6-tetraones structurally related to granulatimide

…, A Loynel, P Casara, B Pfeiffer, M Prudhomme

Index: Henon, Helene; Anizon, Fabrice; Kucharczyk, Nathalie; Loynel, Armelle; Casara, Patrick; Pfeiffer, Bruno; Prudhomme, Michelle Synthesis, 2006 , # 4 p. 711 - 715

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Citation Number: 11

Abstract

Abstract Dipyrrolo [3, 4-a: 3, 4-c] carbazole-1, 3, 4, 6-tetraones can be considered as granulatimide analogues. In view of structure-activity relationship studies in these series, a parallel liquid-phase microwave-assisted synthesis was developed to generate a small library of compounds bearing various substituents at positions 8, 9, 10, or 11 on the aromatic framework.