Chemoselective Reduction of Phenyl Ketones with Amino Alcohol–Borane Complexes

…, T Wakasugi, K Ito, A Hirao, S Nakahama

Index: Itsuno, Shinichi; Wakasugi, Takashi; Ito, Koichi; Hirao, Akira; Nakahama, Seiichi Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 6 p. 1669 - 1673

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Citation Number: 14

Abstract

A new reducing agent was prepared from borane and amino alcohols. The reagent is very effective for chemoselective reduction of ketones in the presence of esters, oxime ethers, tertiary amides, nitriles, halides, and acyl chlorides. The polymeric reagent prepared from borane and polymer-supported amino alcohol was also prepared easily. Aldehydes are highly selectively reduced to primary alcohols in the presence of ketone with the polymeric ...