An asymmetric synthesis of 2, 4-dimethylvalerolactone and mevalonolactone using chiral binaphtyldiamine derivatives

Y Kawakami, J Hiratake, Y Yamamoto

Index: Kawakami, Yukio; Hiratake, Jun; Yamamoto, Yukio; Oda, Jun'ichi Journal of the Chemical Society, Chemical Communications, 1984 , # 12 p. 779 - 781

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Citation Number: 31

Abstract

Syntheses of optically active lactones through discrimination chiral imides3 have also been reported. The selective ring between enantiotopic groups have been successfully achieved opening of prochiral cyclic acid anhydrides has been attemp- using dehydrogenases and hydrolases.1 Non-enzymic asym- ted4 but the selectivity was too low for efficient syntheses of metric syntheses involving selective use of a chiral 1,3- optically active lactones. We ...