Abstract 5-(2-Aminothiazol-4-yl)-8-hydroxyquinoline 2 has been synthesized by treating thiourea with 5-chloroacetyl-8-hydroxyquinoline 1. The amine 2 was treated with aromatic aldehydes to furnish schiff bases 6a-c which on treatment with phenyl isothiocyanate gave the corresponding thiazolo-s-triazines 7a-c. Reaction of 2 with phenyl isothiocyanate gave the corresponding aminocarbothiamide derivative 8 which on reaction with malonic acid ...
