Bulletin of the Chemical Society of Japan

A New Rearrangement Reaction of β-Hydroxy-α-amino Acid N-Carboxy Anhydrides to 2-Oxazolidone Derivatives

T Saito

Index: Saito,T. Bulletin of the Chemical Society of Japan, 1964 , vol. 37, p. 624 - 628

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Citation Number: 8

Abstract

An a-amino acid./V-carboxy anhydride polymerizes into poly-a-amino acid, which is a model substance of protein. The synthesis of/3-hydroxyl-containing poly-a-amino acids is of interest, because the polymers provide models of water-soluble proteins. Polymers containing protected ß-hydroxyl groups, viz., poly-0-acetyl-DL-serine, poly-O-acetyl-L-serine, 2'33 and poly-0-acetyl-L-threonine, 35 have been prepared by the polymerization of the ...