Abstract A strategy for encouraging the formation of extended water arrays is presented, in which molecules that contain a 1, 4-dihydroquinoxaline-2, 3-dione core are used as supramolecular hosts for the accommodation of guest water molecules and arrays. These molecules were selected as they contain a hydrophilic oxalamide-based “terminus” that allows water molecules to hydrogen-bond to the host organic molecules as well as to ...