Synthesis and in vitro pharmacological behavior of platinum (II) complexes containing 1, 2-diamino-1-(4-fluorophenyl)-2-alkanol ligands

…, B Angermaier, B Kircher, R Gust

Index: Dufrasne, Francois; Gelbcke, Michael; Schnurr, Beate; Gust, Ronald Archiv der Pharmazie, 2002 , vol. 335, # 5 p. 229 - 239

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Citation Number: 7

Abstract

In continuation of our effort to optimize the pharmacological profile of [1, 2-diamino-1, 2-bis (4-fluorophenyl) ethane] dichloridoplatinum (II) complexes, we synthesized [1, 2-diamino-1- (4-fluorophenyl) alkanol] dichloridoplatinum (II) analogs. The aim of this study was to