e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Facile Synthesis and In??Vitro Antimalarial Activity of Novel α??Hydroxy Hydrazonates

M Khankischpur, FK Hansen, R Meurer…

Index: Mitsui Toatsu Chem. Patent: DE2944783 , 1980 ; Chem.Abstr., 1980 , vol. 93, # 167904

Full Text: HTML

Citation Number: 3

Abstract

... Volume: Issue: Page ... Chemistry. ... Colorless solid, yield: 37%; mp: 107.8°C; IR ν max (KBr) cm −1 : 3364 (NH), 3310 (OH), 1723 (C O), 1648 (C N); ratio E/Z = 93:7; 1 H-NMR (400 MHz, DMSO-d 6 ), δ (ppm): E-isomer: 0.82 (t, J = 7.1 Hz, 3H), 1.15 (t, J = 7.1 Hz, 3H), 1.23 (t, J = 7.1 ...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

ethyl 2-[2-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazinyl]-2-oxoacetate Structure

ethyl 2-[2-[5-[...

Ethoxalyl chloride Structure

Ethoxalyl chloride

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

ethyl 2-[2-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazinyl]-2-oxoacetate Structure

ethyl 2-[2-[5-[...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitroanilino]formamide Structure

N-[5-[2-chloro-...

Formic Acid Structure

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitroanilino]formamide Structure

N-[5-[2-chloro-...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

N'-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]-2-methylpropanehydrazide Structure

N'-[5-[2-chloro...

2-Methylpropanoyl chloride Structure

2-Methylpropano...

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

N'-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]-2-methylpropanehydrazide Structure

N'-[5-[2-chloro...

Chloroacetyl chloride Structure

Chloroacetyl ch...

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

2-chloro-N'-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]acetohydrazide Structure

2-chloro-N'-[5-...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

2-chloro-N'-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]acetohydrazide Structure

2-chloro-N'-[5-...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

methyl N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitroanilino]carbamate Structure

methyl N-[5-[2-...

Methyl chloroformate Structure

Methyl chloroformate

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

methyl N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitroanilino]carbamate Structure

methyl N-[5-[2-...

Ethyl chloroformate Structure

Ethyl chloroformate

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

ethyl N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitroanilino]carbamate Structure

ethyl N-[5-[2-c...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

ethyl N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitroanilino]carbamate Structure

ethyl N-[5-[2-c...

2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)benzene Structure

2-chloro-1-(3,4...

~%

N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]-2-methoxyacetohydrazide Structure

N-[5-[2-chloro-...

Methoxyacetyl chloride Structure

Methoxyacetyl c...

[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]hydrazine Structure

[5-[2-chloro-4-...

~%

N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrophenyl]-2-methoxyacetohydrazide Structure

N-[5-[2-chloro-...