Abstract-2, 5-Dimethoxy-2-(dimethoxymethyl) tetrahydrofuran 1 reacted with anthranilic acid alkyl esters 2 in boiling acetic acid to give 2-(2-formylpyrrol-1-yl) benzoic acid esters 3. The reductive amination of 3 with primary arylalkylamines 4 led to 2-{2-[(arylalkylamino) methyl] pyrrol-1-yl}-benzoic acids esters 5. Heating of the aminoesters 5 in xylene under reflux resulted in 5-(arylalkyl)-4, 5-dihydro-6H-pyrrolo [1, 2-a][1, 4] benzodiazepin-6-ones 7. ...
