In our investigation of dipeptide nitrogen mustards, we have synthesized the optical arid position isomers of S-[bis (2-chloroethyl) aniinobenzoyl] glutamic acid. 2 The biological activities of thew dipeptide nitrogen inustards and their benzyl2" and ethyl2 ester., were htutlied in niicrobial systems and in KB line cell culture in which moderate activities were demonstrated. In 1 hr Ehrlich ahcites mouse tunior, tlie antineoplastic. xctivitiez: ire largely ...
