Diastereoface-selective Pd2+-promoted cycloalkenylation reaction (22→ 24) has been employed as the key step for a conceptually new and highly diastereocontrolled formal total synthesis of−-stemodin (1). Interestingly, the synthetic intermediates (12) and its ...
[Belliotti, Thomas R.; Kesten, Suzanne R.; Rubin, John R.; Wustrow, David J.; Georgic, Lynn M.; Zoski, Kim T.; Akunne, Hyacinth C.; Wise, Lawrence D. Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 18 p. 2403 - 2408]
![2-(1,4-DIOXA-SPIRO[4.5]DEC-8-YL)-ETHANOL Structure](https://image.chemsrc.com/caspic/257/135761-76-1.png)