e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

RSC Advances

Synthesis of diarylalkynes via tandem Sonogashira/decarboxylative reaction of aryl chlorides with propiolic acid

X Li, F Yang, Y Wu

Index: RSC Advances, , vol. 4, # 26 p. 13738 - 13741

Full Text: HTML

Citation Number: 6

Abstract

... RSC Adv., 2014, 4, 13738-13741. ... image file: c3ra47712f-s4.tif. Scheme 4 The controlling experiment. ... Rev., 2009, 109, 5799 CrossRef CAS PubMed . For the review on decarboxylative coupling of alkynyl carboxylic acids, see: K. Park and S. Lee, RSC Adv., 2013, 3, 14165 RSC . ...

1-Chloro-4-methoxybenzene Structure

1-Chloro-4-meth...

4-n-butylchlorobenzene Structure

4-n-butylchloro...

Propiolic acidd Structure

Propiolic acidd

~32%

1-Butyl-4-[(4-methoxyphenyl)ethynyl]benzene Structure

1-Butyl-4-[(4-m...

Detail

4-n-butylchlorobenzene Structure

4-n-butylchloro...

Propiolic acidd Structure

Propiolic acidd

~54%

1,1'-Ethyne-1,2-diylbis(4-butylbenzene) Structure

1,1'-Ethyne-1,2...

1-Chloro-4-methoxybenzene Structure

1-Chloro-4-meth...

Chlorobenzene Structure

Propiolic acidd Structure

Propiolic acidd

~10%

Anisole, p-(phenylethynyl)- Structure

Anisole, p-(phe...

Detail

1-Chloro-4-methoxybenzene Structure

1-Chloro-4-meth...

4-n-butylchlorobenzene Structure

4-n-butylchloro...

Propiolic acidd Structure

Propiolic acidd

~10%

1-Butyl-4-[(4-methoxyphenyl)ethynyl]benzene Structure

1-Butyl-4-[(4-m...

Detail

1-Chloro-4-methoxybenzene Structure

1-Chloro-4-meth...

4-Chlorotoluene Structure

4-Chlorotoluene

Propiolic acidd Structure

Propiolic acidd

~10%

1-methoxy-4-[2-(4-methylphenyl)ethynyl]benzene Structure

1-methoxy-4-[2-...

Detail

1-Chloro-4-methoxybenzene Structure

1-Chloro-4-meth...

3-Chloro-o-xylene Structure

3-Chloro-o-xylene

Propiolic acidd Structure

Propiolic acidd

~12%

2-[2-(2,6-dimethylphenyl)ethynyl]-1,3-dimethylbenzene Structure

2-[2-(2,6-dimet...

Detail