Organometallic methylation of nicotine and nicotine N-oxide. Reaction pathways and racemization mechanisms

JI Seeman, HV Secor, CR Howe…

Index: Journal of Organic Chemistry, , vol. 48, # 25 p. 4899 - 4904

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Citation Number: 8

Abstract

... (c) El Din, MG; Knaus, EE; Giam, C.-S. Can. J. Chem. ... Consistent with this proposed chemical reactivity of in- termediates 12 and 13 is the recent report by Newcomb and Burchillz3 that an alkenyllithium amide will cyclize to an organolithium species (eq 5). n n ...