Electrosynthesis of 2??Arylpropionic Acids from α??Methylbenzyl Chlorides and Carbon Dioxide by [Co (Salen)]

…, SK Khaja Lateef, S Jayarama Reddy

Index: Damodar; Krishna Mohan; Khaja Lateef; Jayarama Reddy Synthetic Communications, 2005 , vol. 35, # 9 p. 1143 - 1150

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Citation Number: 11

Abstract

Abstract The electrochemical synthesis of the 2??arylpropionic acid group of nonsteroidal anti?? inflammatory agents such as ibuprofen, naproxen, indoprofen, biprofen, cicloprofen, and fenoprofen has been carried out in dimethylformamide (DMF) containing tetra??n?? butylammonium perchlorate (nBu4NClO4) by electrochemical carboxylation of α?? methylbenzyl chlorides catalyzed by a schiff??base complex [Co (salen)] in an undivided ...