Summary: Substituted ethane-1, l-diphosphonic acids containing a (3-hydroxyl group undergo facile pH-dependent decomposition to phosphoric acid and acetylphosphonate. The decomposition is observed in acidic medium, while the system is stable in basic
[Bougioukou, Despina J.; Mukherjee, Subha; Van Der Donk, Wilfred A. Proceedings of the National Academy of Sciences of the United States of America, 2013 , vol. 110, # 27 p. 10952 - 10957]