Tetrahedron letters

A novel and unusual method for C–N bond formation in 1-substituted-pyrrolidin-2-ones

N Sinha, S Jain, N Anand

Index: Sinha, Neelima; Jain, Sanjay; Anand, Nitya Tetrahedron Letters, 2005 , vol. 46, # 1 p. 153 - 156

Full Text: HTML

Citation Number: 9

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A novel 5-C–N bond forming reaction is reported, which involves heating 1-substituted-pyrrolidin-2-ones with cyclic amines in the presence of a base. This reaction provides a convenient method for the synthesis of 1,5-disubstituted-pyrrolidin-2-ones. ... A novel C–N bond forming ...