Chemistry–A European Journal

One??Step Synthesis of Racemic α??Amino Acids from Aldehydes, Amine Components, and Gaseous CO2 by the Aid of a Bismetal Reagent

T Mita, Y Higuchi, Y Sato

Index: Mita, Tsuyoshi; Higuchi, Yuki; Sato, Yoshihiro Chemistry - A European Journal, 2013 , vol. 19, # 3 p. 1123 - 1128

Full Text: HTML

Citation Number: 23

Abstract

Abstract α-Amino acids are essential resources for human life and are highly useful as building blocks for organic synthesis. The core framework of an α-amino acid can be divided into three basic components: an aldehyde, an amine, and carbon dioxide (CO 2). We report herein that a one-step synthesis of α-amino acids has been successfully achieved from these three basic and inexpensive chemicals with a single operation, in which the mixture ...