Nonpeptide αvβ3 antagonists. Part 11: discovery and preclinical evaluation of potent αvβ3 antagonists for the prevention and treatment of osteoporosis

PJ Coleman, KM Brashear, BC Askew…

Index: Journal of medicinal chemistry, , vol. 47, # 20 p. 4829 - 4837

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Citation Number: 75

Abstract

... Journal of Medicinal Chemistry. ... Departments of Medicinal Chemistry, Bone Biology and Osteporosis Research, Drug Metabolism and Pharmacology, and Molecular Systems, Merck Research Laboratories, West Point, Pennsylvania 19486. J. Med. Chem. ... Chemistry. ...

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Discovery and development of potent LFA-1/ICAM-1 antagonist ...

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