Journal of the American Chemical Society

HYDROXY-AND DIHYDROXYPHENYLETHYLMETHYLAMINES AND THEIR ETHERS

JS Buck

Index: Buck Journal of the American Chemical Society, 1932 , vol. 54, p. 3661,3662

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Citation Number: 14

Abstract

The cinnamic acid in each case was made by the well-known Knoevenagel method, by condensation of the aldehyde with malonic acid in the presence of pyridine, piperidine being used as catalyst. On reduction with 4% sodium amalgam (excess= 4H being used), the corresponding phenylpropionic acid was produced, usually in very good yield. From the acid, the amide was made by heating in a stream of ammonia at 220-230" for two hours, ...