Organic letters

Fluorinated analogues of tert-butyl alcohol as novel protecting groups for use in fluorous synthesis

J Pardo, A Cobas, E Guitián, L Castedo

Index: Pardo, Juan; Cobas, Agustin; Guitian, Enrique; Castedo, Luis Organic Letters, 2001 , vol. 3, # 23 p. 3711 - 3714

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Citation Number: 36

Abstract

A series of fluorous derivatives of tert-butyl alcohol were prepared and evaluated as reagents for the protection of carboxylic acids for use in fluorous synthesis. Alcohol 3b can be employed efficiently to protect and immobilize medium-size nonpolar carboxylic acids ...