Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids

M Kuchař, B Brunová, V Rejholc…

Index: Kuchar; Brunova; Rejholec; et al. Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 1 p. 122 - 136

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Citation Number: 10

Abstract

Abstract The paper describes the reaction of arylacetones IX with triethyl phosphonoacetate, producing esters of 4-aryl-3-methyl-2-butenoic acid, X, and 4-aryl-3-methyl-3-butenoic acid, X'. Their hydrolysis gave a mixture of the isomeric acids I and I', whose composition was investigated by 1 H NMR spectra. Also prepared were 3-methyl-3-phenyl-2-propenoic acids, II, 2-aryl-2-hydroxypropanoic acids, IV, and substituted α-benzyloxyphenylacetic acids, V. ...