Résumé/Abstract 6-Methyl-1, 3-dihydro-4H, 7H-pyrazolo [2, 3-c] pyridine-4-one (4) were synthesized by microwave as well as conventional method. The reaction time reduced 10 times than that of conventional method. The pyrazolo [3, 4-d] dihydrothiazole (8) were synthesized by reacting phenylisothiocyanate with 1-carbethoxy-5-amino-pyrazol-4-ene-3- one and were screened for their antimicrobial activities.