Abstract A short and effective synthesis of ethyl 3-(3-aminophenyl) propanoate is presented, employing a tandem Knoevenagel condensation/alkylidene reduction of 3- nitrobenzaldehyde with Meldrum's acid in TEAF (triethylammonium formate) followed by reduction of the intermediate 3-(3-nitrophenyl) propanoic acid by stannous chloride in ethanol. The use of stannous chloride as the reducing agent in ethanol enabled the ...
