Organic letters

Enzymatic dynamic kinetic resolution of (±)-cis-N-(alkoxycarbonyl) cyclopentane-1, 2-diamines based on spontaneous racemization

FJ Quijada, V Gotor, F Rebolledo

Index: Organic Letters, , vol. 12, # 16 p. 3602 - 3605

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Citation Number: 14

Abstract

... Volume: Page: ... Organic Letters. ... CAL-B,(11) first using ethyl acetate as acyl donor and solvent (Scheme 1, entry 1). Under these conditions, the enzyme catalyzed the acetylation of the amino group of 5a, though with moderate enantioselectivity (E = 48).(12) In an ...